Cutaneous leukocytoclastic vasculitis in the presence of methimazole therapy*
نویسندگان
چکیده
Treatment with antithyroid drugs may be accompanied by side effects. We present a patient diagnosed with Grave's Disease who developed extensive vasculitis in the lower limbs during methimazole use. After suspension of the methimazole and the introduction of prednisone in immunesupressor doses the cutaneous lesions started to involute.
منابع مشابه
Antineutrophilic Cytoplasmic Antibody Positive Vasculitis Associated with Methimazole Use
ANCA-associated vasculitis (AAV) is a rare and potentially life threatening complication associated with antithyroid drug use. It is more commonly reported with propylthiouracil, with fewer cases reported with methimazole use. We present the case of a 55-year-old man with toxic multinodular goiter which was treated with methimazole for 6 months. He developed ANCA positive leukocytoclastic vascu...
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متن کاملAntineutrophil cytoplasmic antibody-positive cutaneous leukocytoclastic vasculitis associated with propylthiouracil therapy.
A dministration of propylthiouracil therapy has been associated with a hypersensitivity syndrome that typically manifests as vasculitis. Most cases of propylthiouracil therapy– induced antineutrophil cytoplasmic antibody (ANCA) positivity react to perinuclear ANCA (p-ANCA). We describe a patient who presented with cutaneous manifestations of propylthiouracil therapy hypersensitivity vasculitis ...
متن کاملCentral nervous system vasculitis after starting methimazole in a woman with Graves' disease.
BACKGROUND Graves' disease (GD), a prototypical autoimmune disorder, is associated with other autoimmune diseases, including vasculitis. Antithyroid drugs, despite their postulated immunosuppressive effects, may cause several autoimmune disorders. Here we describe the first patient with central nervous system (CNS) vasculitis that developed shortly after the start of methimazole (MMI) treatment...
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Anti-tuberculosis drugs frequently result in cutaneous adverse reactions, including pruritus, maculopapular exanthems, and urticaria. However, anti-tuberculosis drug-associated cutaneous leukocytoclastic vasculitis (CLV) has been rarely reported. We describe a case of CLV induced by rifampin and pyrazinamide. A 38-year-old male had been diagnosed with pulmonary tuberculosis two months ago and t...
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عنوان ژورنال:
دوره 88 شماره
صفحات -
تاریخ انتشار 2013